Now showing items 1-16 of 16

    • González, Andrea; Singh, Sandeep Kumar; Churruca Muñoz, Macarena; Maccioni Baraona, Ricardo Benjamín (MDPI, 2022)
      Alzheimer's disease (AD) is a multifactorial neurodegenerative disease characterized by progressive cognitive impairment, apathy, and neuropsychiatric disorders. Two main pathological hallmarks have been described: ...
    • Suazo, José; Smalley, Susan Valerie; Hodgson, María Isabel; Weisstaub, Gerardo; González, Andrea; Santos, José Luis (Sociedad Medica de Santiago, 2014)
      Background: Metabolic Syndrome (MS) is highly prevalent among obese children and adolescents and is considered a predictor for the development of type 2 diabetes mellitus and cardiovascular disease. Obesity is associated ...
    • Cortés, Nicole; Guzmán Martínez, Leonardo; Andrade, Víctor; González, Andrea; Maccioni Baraona, Ricardo (IOS Press, 2019)
      The cyclin-dependent kinase 5 (CDK5) is known as an exceptional component of the CDK family, due to its characteristic regulatory pathways and its atypical roles in comparison to the classical cyclins. Despite its functional ...
    • González, Andrea; Calfio Painemal, Camila Del Pilar; Churruca, Macarena; Maccioni Baraona, Ricardo Benjamin (BMC, 2022)
      Background Alzheimer's disease is the most prevalent cause of dementia in the elderly. Neuronal death and synaptic dysfunctions are considered the main hallmarks of this disease. The latter could be directly associated to ...
    • Campo, Miguel del; Arancibia, Sergio; Nova, Esteban; Salazar, Fabián; González, Andrea; Moltedo, Bruno; Ioannes, Pablo de; Ferreira, Jorge; Manubens, Augusto; Becker, María Inés (Sociedad Médica de Santiago, 2011-02)
    • del Campo, Miguel; Arancibia, Sergio; Nova, Esteban; Salazar, Fabián; González, Andrea; Moltedo, Bruno; Ioannes, Pablo de; Ferreira, Jorge; Manubens, Augusto; Becker, María Inés (2011)
      Hemocyanins, the giant oxygen transporter glycoproteins of diverse mollusks, are xenogenic to the mammalian immune system and they display a remarkable immunogenicity. Therefore they are ideal non-specific immunostimulants ...
    • González, Andrea; Valero Breton, Mayalen; Huerta Salgado, Camila Francisca; Achiardi, Oscar; Simon, Felipe; Cabello Verrugio, Claudio Alejandro (Pagepress, 2021)
      Sarcopenia is a highly prevalent complication of non-alcoholic fatty liver disease (NAFLD). We aimed to conduct a systematic review and meta-analyses to elucidate the exercise training (ET)'s efficacy on NAFLD adult patients' ...
    • Ramírez, Patricia A.; González, Andrea; Botto Mahan, Carezza (Springer, 2013)
      Masking, a type of camouflage, has been argued to function as an antipredator mechanism helping to avoid detection or recognition by a prey or predator. However, research focused on the effects of masking on life history ...
    • Ho Urriola, Judith; Guzmán Guzmán, Iris P; Smalley, Susan V.; González, Andrea; Weisstaub Nuta, Sergio; Domínguez Vásquez, Patricia; Valladares, Macarena; Amador, Paola; Hodgson, María Isabel; Obregón, Ana M.; Santos, José Luis (Elsevier, 2014)
      Objective: The aim of this study was to assess the association between melanocortin-4 receptor (MC4R) rs17782313 alleles with obesity and eating behavior scores in Chilean children. Methods: A case–control study was ...
    • Villanueva Maffei, Julio; González, Andrea; Cornejo, Marco; Núñez, Cristián; Encina, Susana (2006)
      El osteocondroma es la neoplasia benigna más común del esqueleto. En la cabeza se ha descrito su localización en base de cráneo, cara posterior del maxilar, senos maxilares, y en diferentes áreas de la mandíbula, como ...
    • Suazo, José; Smalley, Susan Valerie; Hodgson, María Isabel; Weisstaub Nuta, Sergio; González, Andrea; Santos, José Luis (Sociedad Médica de Santiago, 2014)
      Metabolic Syndrome (MS) is highly prevalent among obese children and adolescents and is considered a predictor for the development of type 2 diabetes mellitus and cardiovascular disease. Obesity is associated with ...
    • Guzmán Martínez, Leonardo; Tapia, José Pablo; Farías, Gonzalo A.; González, Andrea; Estrella, Matías; Maccioni Baraona, Ricardo (IOS Press, 2019)
      The establishment of a molecular biomarker for early detection of Alzheimer's disease (AD) is critical for diagnosis and follow up of patients, and as a quantitative parameter in the evaluation of potential new drugs to ...
    • González, Andrea; Simón, Felipe; Achiardi, Óscar; Vilos, Cristian; Cabrera, Daniel; Cabello Verrugio, Claudio (Hindawi, 2021)
      Sarcopenic obesity (SO) is a combination of obesity and sarcopenia that primarily develops in older people. Patients with SO have high fat mass, low muscle mass, low muscle strength, and low physical function. SO relates ...
    • González, Andrea; Nova, Esteban; Del Campo, Miguel; Manubens, Augusto; Ioannes, Alfredo de; Ferreira, Jorge; Becker, María Inés (Elsevier B.V., 2017)
      © 2017 Elsevier B.V. Hemocyanins have highly conserved copper-containing active sites that bind oxygen. However, structural differences among the hemocyanins of various mollusks may affect their physicochemical properties. ...
    • González, Andrea; Valck, Carolina; Sánchez, Gittith; Härtel, Steffen; Mansilla, Jorge; Ramírez, Galia; Fernández, María Soledad; Arias, José; Galanti Garrone, Norbel; Ferreira, Arturo (American Society of Tropical Medicine and Hygiene, 2015)
      Trypanosoma cruzi calreticulin (TcCRT), a 47-kDa chaperone, translocates from the endoplasmic reticulum to the area of flagellum emergence. There, it binds to complement components C1 and mannan-binding lectin (MBL), thus ...
    • González, Andrea; Härtel, Steffen; Mansilla, Jorge; Sánchez-Valdéz, Fernando; Ferreira, Arturo (Elsevier GmbH, 2018)
      Trypanosoma cruzi calreticulin (TcCalr, formerly known as TcCRT), upon binding to Complement (C) C1 and ficolins, inhibits the classical and lectin pathways and promotes infectivity. This virulence correlates with the ...